MicroRNAs: emerging driver of cancer perineural invasion
نویسندگان
چکیده
منابع مشابه
Expression of microRNAs and protein-coding genes associated with perineural invasion in prostate cancer.
BACKGROUND Perineural invasion (PNI) is the dominant pathway for local invasion in prostate cancer. To date, only few studies have investigated the molecular differences between prostate tumors with PNI and those without it. METHODS To evaluate the involvement of both microRNAs and protein-coding genes in PNI, we determined their genome-wide expression with a custom microRNA microarray and Af...
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Diabetes and perineural invasion are frequently observed in pancreatic cancer. In this study, we tested possible relations between diabetes and perineural invasion in patients with resected pancreatic cancer. We conducted a retrospective study in 544 cases of resected pancreatic adenocarcinoma seen at the University of Texas MD Anderson Cancer Center during 1996-2011. Information on tumor chara...
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Background: Prostate cancer has a propensity to invade and grow along nerves, a phenomenon called perineural invasion (PNI). Recent studies suggest that the presence of PNI in prostate cancer has been associated with cancer aggressiveness.Methods: We investigated the association between PNI and lethal prostate cancer in untreated and treated prostate cancer cohorts: the Swedish Watchful Waiting...
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1Department of Physiology, Center for Integrative Toxicology, 4171 Biomedical Physical Sciences, Michigan State University, East Lansing, MI 48824, USA 2Institute for Chemical Carcinogenesis, State Key Laboratory of Respiratory Disease, Guangzhou Medical University 195, Dongfeng Road West, Guangzhou, Guangdong 510182, China 3Department of Oncologic Sciences, Mitchell Cancer Institute, Universit...
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BACKGROUND Perineural invasion is a common path for cholangiocarcinoma (CCA) metastasis, and it is highly correlated with postoperative recurrence and poor prognosis. It is often an early event in a disease that is commonly diagnosed in advanced stages, and thus it could offer a timely therapeutic and diagnostic target if better understood. This article systematically reviews the progress of CC...
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ژورنال
عنوان ژورنال: Cell & Bioscience
سال: 2021
ISSN: 2045-3701
DOI: 10.1186/s13578-021-00630-4